EGF:
Better than Retinol for Wrinkles
Discover the Power Ingredient that Works Better than Retinol for Wrinkles

In This Article You’ll Learn:
1. Why Do We Get Wrinkles?
2. How Does EGF Work?
3. Why is EGF Better than Retinol/Tretinoin?
Fine lines and wrinkles often start around the eyes; In fact, the skin underneath the eyes is some of the thinnest found on our bodies. It’s not just from rubbing our eyes when we’re tired or tugging when applying concealer to hide those dark circles, wrinkles start forming at the cellular level. The major reason why we get wrinkles is because our skin cells’ turnover cycle slows down.
Why Do We Get Wrinkles?
The skin cell turnover cycle is that rate at which new healthy skin cells are formed and take the place of old dead skin cells. When we are younger our skin cell turnover rate is shorter at around 28 days. However, with natural aging and stress our skin cell turnover rate slows down and wrinkles start to form.
Old, dead skin cells do not absorb or retain hydration as well as young healthy skin cells.
No amount of hydration can stimulate faster turnover. As the old skin cells on the skin surface remain longer due to a slower turnover rate, our skin surface becomes dry and wrinkles start to form.
Moreover, dark spots and uneven skin tone also take longer to clear up with a slower turnover rate.
Although exfoliating and using peels may temporarily help stimulate faster skin cell turnover, it still does not treat the root of the problem. You should only exfoliate once or twice a week to prevent skin damage.
How Does EGF Work?
In 1986, the Nobel Prize in Medicine was awarded to biochemist Stanley Cohen for the discovery of EGF: skincare’s fountain of youth.
EGF is technically a protein and it works at the cellular level to directly help restore a healthy turnover cycle, which provides multiple benefits: from speeding up wound recovery and reducing the appearance of wrinkles, to improving hydration and helping clear dark spots(1).
Our skin naturally makes less collagen after the age of 25(3).
As a skincare ingredient, EGF directly tackles skin aging by stimulating healthy collagen and elastin growth to keep your skin firm and lifted.
Did you know that UV exposure can be responsible for 80% of visible facial aging signs?(4) EGF has also been shown to help prevent UV-induced skin damage also known as photo-aging(1).
Why is EGF Better than Retinols or Tretinoin?
Retinol is a very popular and common ingredient in anti-aging and wrinkle fighting skincare products.
From drugstore products to prescription formulas, retinoids work as an exfoliant, which temporarily triggers a faster turnover rate. However, skin care products formulated with retinoids are not suitable for people with sensitive skin types as it can cause irritation, redness, and dryness.
Also, frequent use of retinoids even for people with healthy normal skin types can lead to sensitivity as well(5).
Tretinoin is a new form of retinoids as a retinoic acid but a study shows that it does not provide any better results than retinol.
In fact, retinol was also better tolerated by the users(6).
On the other hand, EGF is safe for use on sensitive skin.
EGF works deep within the skin layers at the cellular level to nourish skin as a protein rather than exfoliate the surface as a harsh acid. Using exfoliants and harsh retinol products often can cause skin thinning and dryness despite the temporary smoothness.
However, after treating your skin to an EGF-rich serum and cream, your skin is healthier, less prone to dryness and UV damage, which is the most common cause of skin aging(1,4).
However, not all EGF is created equal. The Forté Serum and Forté Cream are made with the highest quality vegan sourced EGF.
According to research, EGF works wonders with hyaluronic acid(2). To create a powerful formula that goes above and beyond, the Forté Serum and Forté Cream are made with sodium hyaluronate, a smaller and more effective form of hyaluronic acid.
After 2 Weeks of Using Cell Forté Skincare*

Feel hydrated, smoother skin

See less fine lines & wrinkles

See brighter,
more even skin

Feel firmer, tighter skin
After 2 Weeks of Using
the Cell Forté Skincare*

feel hydrated, smoother skin

see less fine lines & wrinkles

see brighter, more even skin

feel firmer, tighter skin
Recent Reviews
"I've never had so much success with a serum! My skin scars easily and my skincare regimen has always included things that should have helped to lighten dark spots like vitamin C but I wasn't seeing results. I have dark spots from cystic acne that I've been consistently trying to get clear for about half a year. After 2 weeks my scars look much lighter and my fine lines look smoother."

Michelle H.
Age: 30s
Skin Concerns: Redness & Sensitivity to Most Skincare Products, Oily Skin, Acne & Breakouts
"Love the cell forte serum and cream. I have to admit that I was originally skeptical about serum however the cell forte serum is amazing. The cream leaves me with a natural glow and dewy texture which I absolutely love. I have seen a noticeable difference in the firmness of my skin immediately after using it for 2 weeks. After washing my face, I use the serum followed by the cell forte cream and that's it."

Jennifer T.
Age: 50s
Skin Concerns: Dryness, Dullness & Uneven Skin Tone, Fine Lines & Wrinkles, Sagging Skin
"I like the natural herbal smell and the serum feels so refreshing. The cream did not cause any breakouts and with the serum it actually helped my acne calm down. I struggle with oily skin with fine lines, and after maybe a week I noticed my skin looked and felt noticeably smoother. After using it for 2 weeks my skin looks much healthier and brighter. I will definitely be keeping this in my skincare regimen!"

Marissa P.
Age: 40s
Skin Concerns: Dryness, Fine Lines & Wrinkles, Skin Sagging, Under Eye Dark Circles & Puffiness
1 An, Jae Jin, et al. "Protective effects of skin permeable epidermal and fibroblast growth factor against ultraviolet‐induced skin damage and human skin wrinkles." Journal of cosmetic dermatology 12.4 (2013): 287-295.
2 Lee, Do Hyun, et al. "Improvement in skin wrinkles using a preparation containing human growth factors and hyaluronic acid serum." Journal of Cosmetic and Laser Therapy 17.1 (2015): 20-23.
3 Varani, James, et al. "Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation." The American journal of pathology 168.6 (2006): 1861-1868.
4 Flament, Frederic, et al. "Effect of the sun on visible clinical signs of aging in Caucasian skin." Clinical, cosmetic and investigational dermatology 6 (2013): 221.
5 Steffensen, Inger-Lise, et al. "Adverse local effects of retinol and retinyl esters in the skin. Opinion of the Panel on Food Additives, Flavourings, Processing Aids, Materials in Contact with Food and Cosmetics of the Norwegian Scientific Committee for Food Safety." VKM Report (2013).
6 Bouloc, Anne, Andre Luiz Vergnanini, and Maria Claudia Issa. "A double‐blind randomized study comparing the association of Retinol and LR 2412 with tretinoin 0.025% in photoaged skin." Journal of cosmetic dermatology 14.1 (2015): 40-46.
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